Proteins and aggregates of proteins

	We have studied the mobilities of a number of proteins and their aggregates in air, N₂ and CO₂. A DMA-MS spectrum for lysozyme is shown in the figure [reference 5 in Publications]. Interpreting the measured mobilities as if corresponding to a sphere colliding inelastically with the gas, yields protein densities near 0.95 g/cm³ for a wide range of proteins and their aggregates [reference 6 in Publications]. Larger densities are found for proteins with symmetric structures, whose mobility is more directly related to their surface area, such as the GroEL tetradecamer.

We have studied the mobilities of a number of proteins and their aggregates in air, N₂ and CO₂. A DMA-MS spectrum for lysozyme is shown in the figure [reference 5 in Publications]. Interpreting the measured mobilities as if corresponding to a sphere colliding inelastically with the gas, yields protein densities near 0.95 g/cm³ for a wide range of proteins and their aggregates [reference 6 in Publications]. Larger densities are found for proteins with symmetric structures, whose mobility is more directly related to their surface area, such as the GroEL tetradecamer.

Proteins and aggregates of proteins

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