In modern chemical engineering, important changes in the properties of solids and fluids can be made by changing the energy and composition of the interface. The alteration of bulk phase properties may be much less efficient. As an example small quantities of antifreeze proteins can lower the freezing point of water through interface adsorption. An important application of interfacial effect has been recently demonstrated in Professor Firoozabadi’s group where very small quantities of a biosurfactant gives the same effect as the use of large quantities of alcohols in bulk phase for efficient transport of natural gas, the premium fuel of the twentieth century.