The in vivo work that we do forms a unique bridge between biomedical engineering and experimental neuroscience. Our main emphasis is towards development of NMR methods (at 7T, 9.4T, and 11.7T), although we also cultivate other methods, e.g., electrophysiological and optical techniques. 

When testing and developing all methods we strive to image, either directly or indirectly, cellular energetics.

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Selected publications: 

"Odor Maps of Aldehydes and Esters Revealed by Functional MRI in the Glomerular Layer of the Mouse Olfactory Bulb," F.Q. Xu, N. Liu, L. Kida, D.L. Rothman, F. Hyder, and G.M. Shepherd, Proceedings of the National Academy of Sciences of the United States of America, 100(19), 11029-11034 (2003).

"Brain Temperature Measured by H-1-NMR in Conjunction with a Lanthanide Complex," H. K. F. Trubel, P.K. Maciejewski, J.H. Farber, and F. Hyder, Journal of Applied Physiology 94(4), 1641-1649 (2003).

"Cerebral Energetics and Spiking Frequency: The Neurophysiological Basis of fMRI," A. J. Smith, H. Blumenfeld, K.L. Behar, D.L. Rothman, R.G. Shulman, and F. Hyder, Proceedings of the National Academy of Sciences of the United States of America, 99(16), 10765-10770 (2002).

"Quantitative Functional Imaging of the Brain: Towards Mapping Neuronal Activity by BOLD fMRI," F. Hyder, I. Kida, K.L. Behar, R.P. Kennan, P.K. Maciejewski, and D.L. Rothman, NMR in Biomedicine, 14(7-8), 413-431 (2001).

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