Publications:  before 1980

1. Cs. Horváth,"Trennsäulen mit Dünnen Porösen Schichten für die Gaschromatographie (Columns with Thin Porous Layers for the Gaschromatography)," Inaugural Dissertation, Johann Wolfgang Goethe University, Frankfurt, 1963.

2. I. Halász and Cs. Horváth, "Thin-Layer Graphited Carbon Black as the Stationary Phase for Capillary Columns in Gas Chromatography", Nature, 197, 1963, 71-72.

3. I. Halász and Cs. Horváth, "Open Tube Columns with Impregnated Thin Layer Support for Gas Chromatography," Anal. Chem., 35, 1963, 499-505.

4. I. Halász, E. Heine, Cs. Horváth and H.-G. Sternagel, "Gaschromatographische Analyse von C1-C7-Kohlenwasserstoffgemischen mit 'Festschicht'- und 'gepackten' Kapillarkolonnen," Brennst.-Chem., 44, 1963, 387-389.

5. I. Halász and Cs. Horváth, "Micro Beads Coated with a Porous Thin Layer as Column Packing in Gas Chromatography. Some Properties of Graphited Carbon Black as the Stationary Phase," Anal. Chem., 36, 1964, 1178-1186.

6. I. Halász and Cs. Horváth, "Porous Layer Glass Bead Column Packing in Gas Adsorption Layer Chromatography," Anal. Chem., 36, 1964, 2226-2229.

7. Cs. Horváth, "Quantitative Determination of Cholesterol in Auto-Oxidation Mixtures by Thin-Layer Chromatography," J. Chromatogr., 22, 1966, 52-59.

8. Cs. Horváth and S. R. Lipsky, "Use of Liquid Ion-Exchange Chromatography for the Separation of Organic Compounds," Nature, 211, 1966, 748-749.

9. S. R. Lipsky, Cs. Horváth and W. J. McMurray, "Utilization of System Employing the Selective Permeation of Helium through a Unique Membrane of Teflon as an Interface for Gas Chromatograph and Mass Spectrometer," Anal. Chem., 38, 1966, 1585-1587.

10. Cs. Horváth, "Columns in Gas Chromatography", The Practice of Gas Chromatography, L. S. Ettre and A. Zlatkis (Editors), Wiley Interscience, N. Y., 1967, pp. 129-238.

11. Cs. Horváth, B. A. Preiss and S. R. Lipsky, "Fast Liquid Chromatography: An Investigation of Operating Parameters and the Separation of Nucleotides on Pellicular Ion Exchangers", Anal. Chem., 39, 1967, 1422-1428.

12. S. R. Lipsky, W. J. McMurray and Cs. Horváth, "The Analysis of Complex Organic Compounds by Fast-electrical-scanning High-resolution Mass Spectrometry and Gas Chromatography", Gas Chromatography 1966. Proceedings of the Sixth International Symposium on Gas Chromatography and Associated Techniques , A. B. Littlewood (Editor), Elsevier, Amsterdam, 1967, pp. 299-317.

13. Cs. Horváth and S. R. Lipsky, "Peak Capacity in Chromatography," Anal. Chem., 39, 1967, 1893.

14. Cs. Horváth and S. R. Lipsky, "Column Design in High Pressure Liquid Chromatography," J. Chromat. Sci., 7, 1969, 109-116.

15. Cs. Horváth and S. R. Lipsky, "Rapid Analysis of Ribonucleosides and Bases at the Picomole Level Using Pellicular Cation Exchange Resin in Narrow Bore Columns," Anal. Chem., 41, 1969, 1227-1234.

16. S. R. Lipsky, R. J. Cushley, Cs. Horváth and W. J. McMurray, "Analysis of Lunar Material for Organic Compounds," Science, 167, 1970, 778-779.

17. Cs. Horváth, A. Sardi and B. A. Solomon, "Enzyme Reactor Tubes: Effect of Diffusion and Slug Flow," Physiol. Chem. & Physics, 4, 1972, 125-130.

18. Cs. Horváth and B. A. Solomon, "Open Tubular Heterogeneous Enzyme Reactors: Preparation and Kinetic Behavior," Biotechnol. Bioeng., 14, 1972, 885-914.

19. Cs. Horváth, L. H. Shendalman and R. T. Light, "Open Tubular Heterogeneous Enzyme Reactors: Analysis of a Theoretical Model," Chem. Eng. Sci., 28, 1973, 375- 388.

20. Cs. Horváth, A. Sardi and J. S. Woods, "L-Asparaginase Tubes: Kinetic Behavior and Application in Physiological Studies," J. Appl. Physiol., 34, 1973, 181-187.

21. Cs. Horváth and M. Sovak, "Membrane Coarctation by Calcium as a Regulator for Bound Enzymes," Biochim. Biophys. Acta, 298, 1973, 850-860.

22. Cs. Horváth and J.-M. Engasser, "Pellicular Heterogeneous Catalysts. A Theoretical Study of the Advantages of Shell Structured Immobilized Enzyme Particles," Ind. Eng. Chem. Fundam., 12, 1973, 229-235.

23. Cs. Horváth, "High-Performance Ion-Exchange Chromatography with Narrow-Bore Columns: Rapid Analysis of Nucleic Acid Constituents at the Subnanamole Level", Methods of Biochemical Analysis, D. Glick (Editor), Wiley, N. Y., 21, 1973, pp. 79-154.

24. Cs. Horváth, "Pellicular Ion Exchange Resins in Chromatography", Ion Exchange and Solvent Extraction, J. A. Marinsky and Y. Marcus (Editors), M. Dekker, N.Y., 5, 1973, pp. 207-260.

25. B. L. Karger, L. R. Snyder and Cs. Horváth, Introduction to Separation Science, Wiley, N.Y., 1973.

26. Cs. Horváth, B. A. Solomon and J.-M. Engasser, "Measurement of Radial Transport in Slug Flow Using Enzyme Tubes," Ind. Eng. Chem. Fundam., 12, 973, 431-439.

27. J.-M. Engasser and Cs. Horváth, "Effect of Internal Diffusion in Heterogeneous Enzyme Systems: Evaluation of True Kinetic Parameters and Substrate Diffusivity," J. Theor. Biol., 42, 1973, 137-155.

28. Cs. Horváth and J.-M. Engasser, "External and Internal Diffusion in Heterogeneous Enzymes Systems," Biotechnol. Bioeng., 16, 1974, 909-923.

29. Cs. Horváth and B. A. Solomon, "Open Tubular Heterogeneous Enzyme Reactors", Enzyme Engineering, E. K. Pye and L. B. Wingard, Jr. (Editors), Plenum Press, N.Y., 2, 1974, pp. 259-267.

30. Cs. Horváth, "Theory and Practice of Gas Chromatography", Gas Chromatographic Applications in Microbiology and Medicine, B. M. Mitruka (Editor), Wiley, N. Y., 1974, pp. 27-57.

31. Cs. Horváth, "Pellicular Immobilized Enzymes," Biochim. Biophys. Acta, 358, 1974, 164-177.

32. J.-M. Engasser and Cs. Horváth, "Buffer-Facilitated Proton Transport pH Profile of Bound Enzymes," Biochim. Biophys. Acta, 358, 1974, 178-192.

33. J.-M. Engasser and Cs. Horváth, "Facilitated Diffusion with Consecutive Reaction: Optimal Carrier Affinity," Arch. Biochem. Biophys., 164, 1974, 37-42.

34. J.-M. Engasser and Cs. Horváth, "Inhibition of Bound Enzymes I. Antienergistic Interaction of Chemical and Diffusional Inhibition," Biochemistry, 13, 1974, 3845-3849.

35. J.-M. Engasser and Cs. Horváth, "Inhibition of Bound Enzymes. II. Characterization of Product Inhibition and Accumulation," Biochemistry, 13, 1974, 3849-3854.

36. J.-M. Engasser and Cs. Horváth, "Inhibition of Bound Enzymes. III. Diffusion Enhanced Regulatory Effect with Substrate Inhibition," Biochemistry , 13, 1974, 3855-3859.

37. Cs. Horváth, "Pellicular Ion Exchangers," Bonded Stationary Phases in Chromatography, Ann Arbor Science, Ann Arbor, MI, (1974), pp. 59-91.

38. J.-M. Engasser and Cs. Horváth, "Dynamic Role of Buffers: Facilitated Transport of Protons, Weak Acids and Bases," Physiol. Chem. & Phys., 6, 1974, 541-543.

39. J.-M. Engasser and Cs. Horváth, "A Simple Additivity Relation for Analysis of Heterogeneous Catalytic Reactors with First Order Reaction," Chem. Eng. Sci., 29, 1974, 2259-2262.

40. Cs. Horváth, L. S. Ettre and J. E. Purcell, "Support-Coated Open Tubular Columns. A Decade of Progress," Amer. Lab., 6, 1974, 75-86.

41. J.-M. Engasser and Cs. Horváth, "Electrostatic Effects on the Kinetics of Bound Enzymes" Biochem. J., 145, 1975, 431-435.

42. L. S. Ettre and Cs. Horváth, "Foundations of Modern Liquid Chromatography," Anal. Chem., 47, 1975, 422A-434A.

43. J.-M. Engasser and Cs. Horváth, "Efficiency of Mass and Momentum Transport in Homogeneous and Two-Phase Flow," Ind. Eng. Chem. Fundam., 14, 1975, 107-110.

44. H. Wan and Cs. Horváth, "Behavior of Soluble and Immobilized Acid Phosphatase in Hydro-Organic Media," Biochim. Biophys. Acta, 410, 1975, 135-144.

45. J.-M. Engasser and Cs. Horváth, "Diffusion and Kinetics with Immobilized Enzymes," in L. B. Wingard, Jr., E. Katchalski-Katzir and L. Goldstein (Editors), Applied Biochemistry and Bioengineering, Volume 1, Immobilized Enzyme Principles, Academic Press, New York, 1976, pp. 127-220.

46. J.-M. Engasser and Cs. Horváth, "Dynamic Role of Buffers in Heterogeneous Enzyme Systems," in D. Thomas and J. Kernevez (Editors), Analysis and Control of Immobilized Enzyme Systems, Elsevier, New York, 1976, pp. 187-197.

47. R. W. Stout, A. R. Cashmore, J. K. Coward, Cs. Horváth, and J. R. Bertino, "Separation of Substituted Pteroyl Monoglutamates and Pteroyl Oligo- -L-Glutamates by High Pressure Liquid Chromatography," Anal. Biochem., 71, 1976, 119-124.

48. R. W. Stout, R. J. Michelot, I. Molnár, Cs. Horváth and J. K. Coward, "An Analytical Method for the Separation of Dopamine Metabolites in Cellular Extracts by High- Pressure Liquid Chromatography," Anal. Biochem., 76, 1976, 330-341.

49. L. León, S. Narayanan, R. Dellenbach and Cs. Horváth, "Immobilized Glucose Oxidase Used in the Continuous-Flow Determination of Serum Glucose," Clin. Chem., 22, 1976, 1017-1023.

50. Cs. Horváth, "Factors Affecting Enzyme Kinetics in Heterogeneous Systems," in J. Mathieu (Editor), Proc. Table Ronde Roussel Uclaf on Polymer Bound Molecules, Roussel Uclaf, Paris, 1976, pp. 38-42.

51. Cs. Horváth, H. Pedersen, K. Kalghatgi and J. R. Bertino, "Biochemical Reactors for Potential Use in Cancer Chemotherapy," in S. Saha (Editor), Proc. 4th New Engl. Bioeng. Conf., Pergamon Press, New York, 1976, pp. 287-290.

52. I. Molnár and Cs. Horváth, "Reverse-Phase Chromatography of Polar Biological Substances: Separation of Catechol Compounds by High-Performance Liquid Chromatography," Clin. Chem., 22, 1976, 1497-1502.

53. J. R. Bertino, J. K. Coward, A. Cashmore, Chello, S. Panichajakul, Cs. Horváth and R. W. Stout, "Polyglutamate Forms of Folate: Natural Occurrence and Role as Substrates in Mammalian Cells," Biochem. Soc. Trans., 4, 1976, 853-856.

54. Cs. Horváth, W. Melander and I. Molnár, "Solvophobic Interactions in Liquid Chromatography with Nonpolar Stationary Phases," J. Chromatogr., 125, 1976, 129- 156.

55. Cs. Horváth and H.-J. Lin, "Movement and Band Spreading of Unsorbed Solutes in Liquid Chromatography," J. Chromatogr., 126, 1976, 401-420.

56. J.-M. Engasser, M. Flamm and Cs. Horváth, "Hormone Regulation of Cellular Metabolism: Interplay of Membrane Transport and Consecutive Enzymic Reaction," J. Theor. Biol., 67, 1977, 433-445.

57. Cs. Horváth and H.-J. Lin, "A Simple Three-Parameter Equation of State with Critical Compressibility-Factor Correlation," Can. J. Chem. Eng., 55, 1977, 450-456.

58. Cs. Horváth, W. Melander and I. Molnár, "Liquid Chromatography of Ionogenic Substances with Nonpolar Stationary Phases", Anal. Chem., 49, 1977, 142-154.

59. W. Melander and Cs. Horváth, "Salt Effects on Hydrophobic Interactions in Precipitation and Chromatography of Proteins: An Interpretation of the Lyotropic Series," Arch. Biochem. Biophys., 183, 1977, 200-215.

60. L. León, M. Sansur, L. R. Snyder and Cs. Horváth, "Continuous-Flow Analysis for Glucose, Triglycerides, and ATP with Immobilized Enzymes in Tubular Form," Clin. Chem., 23, 1977, 1556-1562.

61. Cs. Horváth and H. Pedersen, "Immobilized Enzymes in Continuous-Flow Analysis," Proceedings of the 7th Technicon Congress, Mediad, Inc., Tarrytown, New York, 1977, pp. 86-95.

62. I. Molnár and Cs. Horváth, "Separation of Amino Acids and Peptides on Non-Polar Stationary Phases by High-Performance Liquid Chromatography," J. Chromatogr., 142, 1977, 623-640.

63. I. Molnár and Cs. Horváth, "Rapid Separation of Urinary Acids by High-Performance Liquid Chromatography," J. Chromatogr., 143, 1977, 391-400.

64. I. Molnár and Cs. Horváth, "Rapid Analysis of Peptide Mixtures by High Performance Liquid Chromatography with Nonpolar Stationary Phases," in M. Goodman and J. Meienhofer (Editors), Peptides, Halsted (Wiley), New York, 1977, pp. 48-51.

65. Cs. Horváth and W. Melander, "Liquid Chromatography with Hydrocarbonaceous Bonded Phases; Theory and Practice of Reversed Phase Chromatography," J. Chromatogr. Sci., 15, 1977, 393-404.

66. Cs. Horváth, W. Melander, I. Molnár and Molnár, "Enhancement of Retention by Ion-Pair Formation in Liquid Chromatography with Nonpolar Stationary Phases," Anal. Chem., 49, 1977, 2295-2305.

67. H. Pedersen and Cs. Horváth, "Tubular Wall Reactors with Immobilized Enzymes for Segmented-Flow Analysis," AIChE, 70th Natl. Meeting, New York, 1977.

68. W. Melander and Cs. Horváth, "Effect of Neutral Salts on the Formation and Dissociation of Protein Aggregates," J. Solid-Phase Biochem., 2, 1977, 141-161.

69. H. Pedersen, Cs. Horváth and J. R. Bertino, "Immobilized Enzymes in Tubes and Hollow Fibers for Clinical Applications," in E. K. Pye and H. Weetall (Editors), Enzyme Engineering, Plenum Press, New York, 3, 1978, pp. 397-408.

70. I. Molnár, Cs. Horváth and Jatlow, "Separation of Urinary Aromatic Acids and Measurement of Vanilmandelic Acid by High-Performance Liquid Chromatography," Chromatographia, 11, 1978, 260-265.

71. I. Molnár and Cs. Horváth, "Catecholamines and Related Compounds Effect of Substituents on Retention in Reversed-Phase Chromatography," J. Chromatogr., 145, 1978, 371-381.

72. Cs. Horváth and H.-J. Lin, "Band Spreading in Liquid Chromatography General Plate Height Equation and a Method for the Evaluation of the Individual Plate Height Contributions," J. Chromatogr., 149, 1978, 43-70.73.

73. J. R. Bertino, S. Condos, Cs. Horváth, K. Kalghatgi and H. Pedersen, "Immobilized Carboxypeptidase G1 in Methotrexate Removal," Cancer Res., 38, 1978, 1936-1941.

74. W. Melander, D. E. Campbell and Cs. Horváth, "Enthalpy-Entropy Compensation in Reversed-Phase Chromatography," J. Chromatogr., 158, 1978, 215-225.

75. H. Pedersen, Cs. Horváth, and C. M. Ambrus, "Preparation of Immobilized L- Phenylalanine Ammonia-Lyase in Tubular Form for Depletion of L-Phenylalanine," Res. Comm. Chem. Pathol. Pharmacol., 20, 1978, 559-569.

76. W. Melander and Cs. Horváth, "Hydrophobic Interactions in Purification and Utilization of Enzymes," in G. H. Broun, G. Menecke and L. B. Wingard, Jr. (Editors), Enzyme Engineering, Plenum Press, New York, 4, 1978, pp. 355-363.

77. Cs. Horváth and W. Melander, "Reversed-Phase Chromatography and the Hydrophobic Effect," Amer. Lab, 10, 1978, 17-36.

78. C. M. Ambrus, J. L. Ambrus, Cs. Horváth, H. Pedersen, S. Sharma, C. Kant, E. Mirand, R. Guthrie and T. Paul, "Phenylalanine Depletion for the Management of Phenylketonuria: Use of Enzyme Reactors with Immobilized Enzymes," Science, 201, 1978, 837-839.

79. Cs. Horváth, in L. S. Ettre and A. Zlatkis (Editors), 75 Years of Chromatography, Elsevier, Amsterdam, 1979, pp. 151-158.

80. B. K. Chen , Cs. Horváth and J. R. Bertino, "Multivariate Analysis and Quantitative Structure-Activity Relationships. Inhibition of Dihydrofolate Reductase and Thymidylate Synthetase by Quinazolines," J. Med. Chem., 22, 1979, 483-491.

81. K. Kalghatgi, B. A. Moroson, Cs. Horváth and J. R. Bertino, "Enhancement of Antitumor Activity of 2,4-Diamino-5-(3',4'-dichlorophenyl)-6-methypyrimidine and Baker's Antifol (Triazinate) with Carboxypeptidase G1," Cancer Res., 39, 1979, 3441-3445.

82. B. T. Bush, J. H. Frenz, W. R. Melander, Cs. Horváth, A. R. Cashmore, R. N. Dryer, J. O. Knipe, J. K. Coward and J. R. Bertino, "Retention Behavior of Pteroyl-Oligo-L- Glutamates in Reversed-Phase Chromatography," J. Chromatogr., 168, 1979, 343- 353.

83 B.-K. Chen and Cs. Horváth, "Evaluation of Substituent Contributions to Chromatographic Retention: Quantitative Structure-Retention Relationships," J. Chromatogr., 171, 1979, 15-28.

84. Cs. Horváth, W. Melander and A. Nahum, "Measurement of Association Constants for Complexes by Reversed-Phase High-Performance Liquid Chromatography," J. Chromatogr., 186, 1979, 371-403.

85. W. R. Melander, B.-K. Chen and Cs. Horváth, "Mobile Phase Effects in Reversed- Phase Chromatography I. Concomitant Dependence of Retention on Column Temperature and Eluent Composition," J. Chromatogr., 185, 1979, 99-109.

86. W. R. Melander, J. Stoveken and Cs. Horváth, "Mobile Phase Effects in Reversed- Phase Chromatography II. Acidic Amine Phosphate Buffers as Eluents," J. Chromatogr., 185, 1979, 111-127.

87. W. R. Melander, A. Nahum and Cs. Horváth, "Mobile Phase Effects in Reversed Phase Chromatography III. Changes in Conformation and Retention of Oligo-(ethyleneglycol) Derivatives with Temperature and Eluent Composition," J. Chromatogr., 185, 1979, 129-152.

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